BRCA

Population-based cancer surveillance provides a quantitative measurement of cancer occurrence in the United States and globally. Core activities of surveillance include measuring cancer incidence and characterizing each cancer with regard to histopathology, stage, and treatment in the context of survival. Cancer surveillance has been crucial in informing policy and practice, as well as clinical and public health efforts to reduce the cancer burden. Surveillance also provides information for generating research hypotheses on cancer causes and outcomes, and for developing and evaluating interventions for cancer prevention and treatment.

Cancer surveillance traditionally is conducted based on tumor anatomic location, histologic features, size, involvement of lymph nodes and distant metastasis (i.e., anatomic stage) at diagnosis. However, within and across cancers, biomarkers can identify heterogeneous subgroups associated…