GSR: Simulator - DUDE-Seq
Attribute | Value |
---|---|
Title | DUDE-Seq |
Short Description | Fast, flexible, and robust denoising of nucleotide sequences |
Long Description | DUDE-Seq considers the correction of errors from nucleotide sequences produced by next-generation sequencing. Our methodology, named DUDE-Seq, is derived from a general setting of reconstructing finite-valued source data corrupted by a discrete memoryless channel and provides an effective means for correcting substitution and homopolymer indel errors. Our experimental studies with real and simulated data sets suggest that the proposed DUDE-Seq outperforms existing alternatives in terms of error-correction capabilities, time efficiency, as boosting the reliability of downstream analyses. Further, DUDE-Seq is universally applicable across different sequencing platforms and analysis pipelines by a simple update of the noise model. |
Homepage | http://data.snu.ac.kr/pub/dude-seq/ |
Citations | Lee B, Moon T, Yoon S, Weissman T, DUDE-Seq: Fast, flexible, and robust denoising for targeted amplicon sequencing., PLoS One, 07-27-2017 [ Abstract, cited in PMC ] |
GSR Certification | This simulator has not yet been evaluated for GSR Certification. Learn more about or request GSR Certification. |
Author verification | The basic description provided was derived from a website or publications by the GSR team and has not yet been verified by the simulation author. To modify this entry or add more information, propose changes to this simulator. |
Attribute Category | Attribute |
---|---|
Target | |
Type of Simulated Data | |
Variations | |
Simulation Method | |
Input | |
Data Type | |
File format | |
Output | |
Data Type | |
Sequencing Reads | |
File Format | |
Sample Type | |
Phenotype | |
Trait Type | |
Determinants | |
Evolutionary Features | |
Demographic | |
Population Size Changes | |
Gene Flow | |
Spatiality | |
Life Cycle | |
Mating System | |
Fecundity | |
Natural Selection | |
Determinant | |
Models | |
Recombination | |
Mutation Models | |
Events Allowed | |
Other | |
Interface | |
Development | |
Tested Platforms | |
Language | |
License | |
GSR Certification |
No example publication using DUDE-Seq has been provided.
Please propose new citations if you are aware of publications that use this software.