GSR: Simulator - DUDE-Seq
| Attribute | Value |
|---|---|
| Title | DUDE-Seq |
| Short Description | Fast, flexible, and robust denoising of nucleotide sequences |
| Long Description | DUDE-Seq considers the correction of errors from nucleotide sequences produced by next-generation sequencing. Our methodology, named DUDE-Seq, is derived from a general setting of reconstructing finite-valued source data corrupted by a discrete memoryless channel and provides an effective means for correcting substitution and homopolymer indel errors. Our experimental studies with real and simulated data sets suggest that the proposed DUDE-Seq outperforms existing alternatives in terms of error-correction capabilities, time efficiency, as boosting the reliability of downstream analyses. Further, DUDE-Seq is universally applicable across different sequencing platforms and analysis pipelines by a simple update of the noise model. |
| Homepage | http://data.snu.ac.kr/pub/dude-seq/ |
| Citations | Lee B, Moon T, Yoon S, Weissman T, DUDE-Seq: Fast, flexible, and robust denoising for targeted amplicon sequencing., PLoS One, 07-27-2017 [ Abstract, cited in PMC ] |
| GSR Certification | This simulator has not yet been evaluated for GSR Certification. Learn more about or request GSR Certification. |
| Author verification | The basic description provided was derived from a website or publications by the GSR team and has not yet been verified by the simulation author. To modify this entry or add more information, propose changes to this simulator. |
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No example publication using DUDE-Seq has been provided.
Please propose new citations if you are aware of publications that use this software.