The joinpoint regression model and permutation tests for identifying changes in trend are described in:

Methods Citation:

Kim HJ, Fay MP, Feuer EJ, Midthune DN. "Permutation tests for joinpoint regression with applications to cancer rates" Statistics in Medicine 2000; 19:335-351: (correction: 2001;20:655).

The present document describes the use of the Joinpoint Regression Program for Windows.

Software Citation:

Joinpoint Regression Program, Version - April 2020; Statistical Methodology and Applications Branch, Surveillance Research Program, National Cancer Institute.