a robust and configurable RNA expression simulator Long Description (required)
CAMPAREE is a RNA expression simulator that is primed using real data to give realistic output. CAMPAREE needs as input a reference genome with transcript annotations as well as fastq files of samples of the species to base the output on. For each sample, CAMPAREE outputs a simulated set of RNA transcripts mimicking expression levels with in the fastq files and accounting for isoform-level expression and allele-specific expression. It also outputs simulated diploid genomes and their corresponding annotations with phased SNP and indel calls in the transcriptome from fastq reads. Additionally the simulation outputs the underlying distributions used for expressing the transcripts. https://github.com/itmat/CAMPAREE
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Summary of Proposed Changes Current Citations/Applications
[Pubmed ID: 34563123 ],
Lahens NF, Brooks TG, Sarantopoulou D, Nayak S, Lawrence C, Mrčela A, Srinivasan A, Schug J, Hogenesch JB, Barash Y, et al. ,
CAMPAREE: a robust and configurable RNA expression simulator. ,
BMC Genomics ,
09-25-2021 ,
https://www.ncbi.nlm.nih.gov/pubmed/?term=34563123, Primary Citation