GSR: Simulator - HaploDX

Basic Package Attributes
AttributeValue
Title HaploDX
Short Description A python library to develop genomic data simulators
Long Description The HaploDX library provides a collection of functions to generate simulated population-specific genomic data in VCF format. The library includes parameters and functions to control mutation rates, linkage disequilibrium strength and block lengths, and number of individuals. To generate genomic data, the HaploDX framework offers a pipeline of functions that can be used to simulate: (1) the allele frequency spectra of different populations; (2) the Hardy-Weinberg principle for genotypes and haplotypes; (3) linkage disequilibrium across different populations.
Keywords GWAS, GWAS Dataset, Linkage Disequilibrium, VCF, Population Genomics, Population Genetics, Allele Frequency Spectrum, Hardy-Weinberg Equilibrium, Genomic Data, Microarray, SNP chips
Version 0.4-beta.1
Project Started 2023
Last Release 1 year, 11 months ago
Homepagehttps://github.com/remytuyeras/HaploDynamics
Citations Remy Tuyeras, How to simulate genomic data?, CTBCS Blog, March 3, 2023 [ Abstract ]
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Author verificationThe basic description provided was derived from a website or publications by the GSR team and has not yet been verified by the simulation author. To modify this entry or add more information, propose changes to this simulator.
Detailed Attributes
Attribute CategoryAttribute
Target
Type of Simulated DataGenotype at Genetic Markers, Diploid DNA Sequence,
VariationsBiallelic Marker, Single Nucleotide Variation, Amino acid variation,
Simulation MethodMachine Learning, Other,
Input
Data TypeAllele Frequencies, Saved simulation, Other,
File format
Output
Data TypeGenotype or Sequence, Mutation, Linkage Disequilibrium,
Sequencing Reads
File FormatVCF,
Sample TypeRandom or Independent,
Phenotype
Trait Type
Determinants
Evolutionary Features
Demographic
Population Size ChangesBottleneck, User Defined,
Gene Flow
Spatiality
Life Cycle
Mating System
Fecundity
Natural Selection
Determinant
Models
Recombination
Mutation ModelsTwo-allele Mutation Model,
Events AllowedVarying Demographic Features, Varying Genetic Features,
Other
InterfaceScript-based,
Development
Tested PlatformsMac OS X, Linux and Unix,
LanguagePython,
LicenseGNU Public License,
GSR Certification

Number of Primary Citations: 1

Number of Non-Primary Citations: 0

No example publication using HaploDX has been provided.

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