PaSS is an effective sequence simulator for PacBio sequencing Long Description (required)
PacBio Sequencing Simulator (PaSS) can learn sequence patterns from PacBio sequencing data currently available. In addition to the distribution of read lengths and error rates, we included a context-specific sequencing error model. Compared to existing PacBio sequencing simulators such as PBSIM, LongISLND and NPBSS, PaSS performed better in many aspects. Assembly tests also suggest that reads simulated by PaSS are the most similar to experimental sequencing data. https://cgm.sjtu.edu.cn/PaSS/
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Summary of Proposed Changes Current Citations/Applications
[Pubmed ID: 31226925 ],
Zhang W, Jia B, Wei C ,
PaSS: a sequencing simulator for PacBio sequencing. ,
BMC Bioinformatics ,
06-21-2019 ,
https://www.ncbi.nlm.nih.gov/pubmed/?term=31226925, Primary Citation
[Pubmed ID: 35041529 ],
Shaw J, Yu YW ,
flopp: Extremely Fast Long-Read Polyploid Haplotype Phasing by Uniform Tree Partitioning. ,
J Comput Biol ,
02-01-2022 ,
https://www.ncbi.nlm.nih.gov/pubmed/?term=35041529, , Application
[Pubmed ID: 35307007 ],
Logan R, Fleischmann Z, Annis S, Wehe AW, Tilly JL, Woods DC, Khrapko K ,
3GOLD: optimized Levenshtein distance for clustering third-generation sequencing data. ,
BMC Bioinformatics ,
03-20-2022 ,
https://www.ncbi.nlm.nih.gov/pubmed/?term=35307007, , Application