GSR: Simulator - PhenotypeSimulator

Basic Package Attributes
AttributeValue
Title PhenotypeSimulator
Short Description flexible simulation of phenotypes from different genetic and non-genetic (noise) components.
Long Description PhenotypeSimulator allows for the simulation of complex phenotypes under different models, including genetic variant effects and infinitesimal genetic effects (reflecting population structure) as well as correlated, non-genetic covariates and observational noise effects. Different phenotypic effects can be combined into a final phenotype while controlling for the proportion of variance explained by each of the components. For each component, the number of variables, their distribution and the design of their effect across traits can be customised.
Version 0..3.3
Project Started 2018
Last Release 4 years, 10 months ago
Homepagehttps://github.com/HannahVMeyer/PhenotypeSimulator
Citations Meyer HV, Birney E, PhenotypeSimulator: A comprehensive framework for simulating multi-trait, multi-locus genotype to phenotype relationships., Bioinformatics, 09-01-2018 [ Abstract, cited in PMC ]
GSR CertificationGSR-certified

Accessibility
Documentation
Application
Support

Last evaluated06-22-2021 (1005 days ago)
Author verificationThe basic description provided was derived from a website or publications by the GSR team and has not yet been verified by the simulation author. To modify this entry or add more information, propose changes to this simulator.
Detailed Attributes
Attribute CategoryAttribute
Target
Type of Simulated DataPhenotype,
Variations
Simulation Method
Input
Data Type
File format
Output
Data Type
Sequencing Reads
File Format
Sample Type
Phenotype
Trait Type
Determinants
Evolutionary Features
Demographic
Population Size Changes
Gene Flow
Spatiality
Life Cycle
Mating System
Fecundity
Natural Selection
Determinant
Models
Recombination
Mutation Models
Events Allowed
Other
Interface
Development
Tested PlatformsWindows, Mac OS X, Linux and Unix,
LanguageR,
LicenseOther,
GSR CertificationAccessibility, Documentation, Application, Support,

Number of Primary Citations: 1

Number of Non-Primary Citations: 2

The following 2 publications are selected examples of applications that used PhenotypeSimulator.

2022

Zeng B, Bendl J, Kosoy R, Fullard JF, Hoffman GE, Roussos P, Multi-ancestry eQTL meta-analysis of human brain identifies candidate causal variants for brain-related traits., Nat Genet, 02-01-2022 [Abstract]

Swart Y, van Eeden G, Uren C, van der Spuy G, Tromp G, Möller M, GWAS in the southern African context., PLoS One, 09-28-2022 [Abstract]


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