GSR: Simulator - Rose
|Short Description||Random model of sequence evolution|
|Long Description||Rose implements a new probabilistic model of the evolution of RNA-, DNA-, or protein-like sequences. Guided by an evolutionary tree, a family of related sequences is created from a common ancestor sequence by insertion, deletion and substitution of characters. During this artificial evolutionary process, the `true' history is logged and the `correct' multiple sequence alignment is created simultaneously. The model also allows for varying rates of mutation within the sequences, making it possible to establish so-called sequence motifs. The data created by Rose are suitable for the evaluation of methods in multiple sequence alignment computation and the prediction of phylogenetic relationships. It can also be useful when teaching courses in or developing models of sequence evolution and in the study of evolutionary processes.|
|Last Release||23 years, 6 months ago|
|Citations||Stoye J, Evers D, Meyer F, Rose: generating sequence families., Bioinformatics, 01-01-1998 [ Abstract, cited in PMC ]|
|Author verification||The basic description provided was derived from a website or publications by the GSR team and has not yet been verified by the simulation author. To modify this entry or add more information, propose changes to this simulator.|
|Type of Simulated Data||Haploid DNA Sequence, RNA, Protein Sequence,|
|Variations||Insertion and Deletion,|
|File format||Program Specific,|
|Data Type||Genotype or Sequence,|
|Population Size Changes|
|Mutation Models||Markov DNA Evolution Models, Indels and Others,|
|Tested Platforms||Linux and Unix, Solaris,|
|Language||C or C++,|
No example publication using Rose has been provided.
Please propose new citations if you are aware of publications that use this software.