SANTA simulates the evolution of gene sequences. Long Description (required)
SANTA is JAVA software application that simulates the evolution of a population of gene sequences forwards through time. It models the underlying biological processes as discrete components; replication (including recombination), mutation (including indels), fitness and selection. SANTA is easy to use and is well-suited to simulate pathogen evolution according to different scenarios. https://github.com/santa-dev/santa-sim u241918@bcm.edu
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Summary of Proposed Changes Current Citations/Applications
[Pubmed ID: 30863552 ],
Jariani A, Warth C, Deforche K, Libin P, Drummond AJ, Rambaut A, Matsen Iv FA, Theys K ,
SANTA-SIM: simulating viral sequence evolution dynamics under selection and recombination. ,
Virus Evol ,
03-08-2019 ,
https://www.ncbi.nlm.nih.gov/pubmed/?term=30863552, Primary Citation
[Pubmed ID: 35137080 ],
Lytras S, Hughes J, Martin D, Swanepoel P, de Klerk A, Lourens R, Kosakovsky Pond SL, Xia W, Jiang X, Robertson DL ,
Exploring the Natural Origins of SARS-CoV-2 in the Light of Recombination. ,
Genome Biol Evol ,
02-04-2022 ,
https://www.ncbi.nlm.nih.gov/pubmed/?term=35137080, , Application
[Pubmed ID: 37421655 ],
Jones BR, Joy JB ,
Inferring Human Immunodeficiency Virus 1 Proviral Integration Dates With Bayesian Inference. ,
Mol Biol Evol ,
08-03-2023 ,
https://www.ncbi.nlm.nih.gov/pubmed/?term=37421655, , Application