GSR: Simulator - SIMLA
Attribute | Value |
---|---|
Title | SIMLA |
Short Description | SIMLA is a SIMuLAtion program that generates data sets of families for use in Linkage and Association studies. |
Long Description | SIMLA is a SIMuLAtion program that generates data sets of families for use in Linkage and Association studies. It allows the user flexibility in specifying marker and disease placement, locus heterogeneity, disequilibrium between markers and between markers and disease loci. Output is in the form of a LINKAGE (Lathrop et al., Proc Natl Acad Sci USA 81, 1984) pedigree file and is easily utilized, either directly or with minimal reformatting, as input for various genetic analysis packages. |
Version | 3.2 |
Project Started | 2005 |
Last Release | 19 years, 2 months ago |
Homepage | http://dmpi.duke.edu/simla-simulation-software-version-32 |
Citations | Schmidt M, Hauser ER, Martin ER, Schmidt S, Extension of the SIMLA package for generating pedigrees with complex inheritance patterns: environmental covariates, gene-gene and gene-environment interaction., Stat Appl Genet Mol Biol, 01-01-2005 [ Abstract, cited in PMC ] |
GSR Certification | This package has been evaluated. No certificates were awarded at this time. |
Last evaluated | 10-01-2020 (1268 days ago) |
Author verification | The basic description provided was derived from a website or publications by the GSR team and has not yet been verified by the simulation author. To modify this entry or add more information, propose changes to this simulator. |
Attribute Category | Attribute |
---|---|
Target | |
Type of Simulated Data | Genotype at Genetic Markers, |
Variations | Biallelic Marker, |
Simulation Method | Gene dropping, |
Input | |
Data Type | |
File format | |
Output | |
Data Type | Genotype or Sequence, Phenotypic Trait, |
Sequencing Reads | |
File Format | Linkage, |
Sample Type | Sibpairs, Trios and Nuclear Families, Extended or Complete Pedigrees, Case-control, |
Phenotype | |
Trait Type | Binary or Qualitative, Quantitative, |
Determinants | Single Genetic Marker, Multiple Genetic Markers, Gene-Gene Interaction, Environmental Factors, Gene-Environment Interaction, |
Evolutionary Features | |
Demographic | |
Population Size Changes | Constant Size, |
Gene Flow | |
Spatiality | |
Life Cycle | |
Mating System | |
Fecundity | |
Natural Selection | |
Determinant | |
Models | |
Recombination | |
Mutation Models | |
Events Allowed | |
Other | |
Interface | Command-line, |
Development | |
Tested Platforms | Windows, Mac OS X, Linux and Unix, Solaris, |
Language | C or C++, |
License | |
GSR Certification |
Number of Primary Citations: 1
Number of Non-Primary Citations: 0
No example publication using SIMLA has been provided.
Please propose new citations if you are aware of publications that use this software.