A program to simulate protein evolution by substitution, insertion and deletion Long Description (required) Protein evolution has been largely modelled by considering the amino acid substitution process; however they have been few studies of the process of insertion and deletion.
Simprot allows for several models of amino acid substitution (PAM, JTT and PMB), allows for gamma distributed sites rates according to Yang's model, and implements a parameterised Qian and Goldstein distribution model for insertion and deletion. http://www.uhnresearch.ca/labs/tillier/software.htm#3 Step 1: Use the attribute tree to add new attributes or remove pre-selected attributes to describe the simulator. Every sub-attribute is selected Not all sub-attributes are selected Fill Clear Expand Collapse Reset Summary of Proposed Changes Step 2: Review list of proposed attribute addition(s) and subtraction(s). Can't Find the Attribute You Are Looking For?
If you would like to propose an attribute that you cannot find in the tree above, or if you would like to add a clarification to one or more attributes for this simulator (e.g. a specific file format for attribute /Output/File Format/Other), please list them in the
Additional Comment box of the Submit tab. Summary of Proposed Changes Current Citations/Applications
SIMPROT: using an empirically determined indel distribution in simulations of protein evolution. BMC Bioinformatics,
https://www.ncbi.nlm.nih.gov/pubmed/?term=16188037, Primary Citation