GSR: Editing - SLiM Simulator

You may request changes to this simulator by navigating to the Basic, Details, and Citations/Applications tabs. When you are finished, open the Submit tab. To return back to the simulator view, click SLiM. Finally, please take note of the GSR simulator privacy policy.
SLiM
A framework for implementing forward genetic simulations, including an interactive development environment and a highly flexible scripting language.
SLiM is an evolutionary simulation framework that combines a powerful engine for population genetic simulations with the capability of modeling arbitrarily complex evolutionary scenarios. Simulations are configured via the integrated Eidos scripting language that allows interactive control over practically every aspect of the simulated evolutionary scenarios. The underlying individual-based simulation engine is highly optimized to enable modeling of entire chromosomes in large populations. For macOS and Linux users, we also provide a graphical user interface for easy simulation set-up, interactive runtime control, and dynamical visualization of simulation output.
3.4
05-20-2013
05-12-2020
https://messerlab.org/slim/
bhaller@mac.com

Attribute Tree Control

Step 1: Use the attribute tree to add new attributes or remove pre-selected attributes to describe the simulator.

Every sub-attribute is selected
Not all sub-attributes are selected
  • Target
    • Type of Simulated Data
      • Genotype at Genetic Markers
      • Diploid DNA Sequence
      • Haploid DNA Sequence
      • RNA
      • Sex Chromosomes
      • Mitochondrial DNA
      • Protein Sequence
      • Sequencing Reads
    • Variations
      • Biallelic Marker
      • Multiallelic Marker
      • Single Nucleotide Variation
      • Amino acid variation
      • Microsatellite
      • Insertion and Deletion
      • CNV
      • Inversion and Rearrangement
      • Alternative Splicing
      • Missing Genotypes
      • Genotype or Sequencing Error
      • Other
  • Simulation Method
    • Standard Coalescent
    • Exact Coalescent
    • Forward-time
    • Resample Existing Data
    • Phylogenetic
    • Gene dropping
    • Other
  • Input
    • Data Type
      • Allele Frequencies
      • Empirical
      • Ancestral Sequence
      • Saved simulation
      • Reference genome
      • Other
    • File format
      • Arlequin
      • CREATE
      • Fstat
      • GDA
      • Genepop
      • MIGRATE
      • MS
      • NEXUS
      • Phylip
      • STRUCTURE
      • XML
      • Program Specific
      • Other
  • Output
    • Data Type
      • Genotype or Sequence
      • Phenotypic Trait
      • Individual Relationship
      • Demographic
      • Mutation
      • Linkage Disequilibrium
      • Diversity Measures
      • Fitness
      • Sequencing Reads
        • Illumina
        • Roche 454
        • SOLiD
        • IonTorrent
        • PacBio
        • Nanopore
        • Other
      • Other
    • File Format
      • Arlequin
      • Fasta or Fastq
      • Fstat
      • Genepop
      • Linkage
      • MIGRATE
      • MS
      • PED
      • Phylip
      • NEXUS
      • STRUCTURE
      • VCF
      • SAM or BAM
      • Program Specific
      • Other
    • Sample Type
      • Random or Independent
      • Sibpairs, Trios and Nuclear Families
      • Extended or Complete Pedigrees
      • Case-control
      • Longitudinal
      • Other
  • Phenotype
    • Trait Type
      • Binary or Qualitative
      • Quantitative
      • Multiple
    • Determinants
      • Single Genetic Marker
      • Multiple Genetic Markers
      • Sex-linked
      • Gene-Gene Interaction
      • Environmental Factors
      • Gene-Environment Interaction
  • Evolutionary Features
    • Demographic
      • Population Size Changes
        • Constant Size
        • Exponential Growth or Decline
        • Logistic Growth
        • Bottleneck
        • Carrying Capacity
        • User Defined
      • Gene Flow
        • Stepping Stone Models
        • Island Models
        • Continent-Island Models
        • Sex or Age-Specific Migration Rates
        • Influenced by Environmental Factors
        • Admixed Population
        • User-defined Matrix
        • Other
      • Spatiality
        • Discrete Models
        • Continuous Models
        • Landscape Factors
    • Life Cycle
      • Discrete Generation Model
      • Age structured
      • Overlapping Generation
      • User-Defined transition matrices
    • Mating System
      • Random Mating
      • Monogamous
      • Polygamous
      • Haplodiploid
      • Selfing
      • Age- or Stage-Specific
      • Assortative or Disassortative
      • Other
    • Fecundity
      • Constant Number
      • Randomly Distributed
      • Individually Determined
      • Influenced by Environment
      • Other
    • Natural Selection
      • Determinant
        • Single-locus
        • Multi-locus
        • Codon-based
        • Fitness of Offspring
        • Phenotypic Trait
        • Environmental Factors
      • Models
        • Directional Selection
        • Balancing Selection
        • Multi-locus models
        • Epistasis
        • Random Fitness Effects
        • Disruptive
        • Phenotype Threshold
        • Frequency-Dependent
        • Other
    • Recombination
      • Uniform
      • Varying Recombination Rates
      • Gene Conversion Allowed
    • Mutation Models
      • Two-allele Mutation Model
      • Markov DNA Evolution Models
      • k-Allele Model
      • Infinite-allele Model
      • Infinite-sites Model
      • Stepwise Mutation Model
      • Codon and Amino Acid Models
      • Indels and Others
      • Heterogeneity among Sites
      • Others
    • Events Allowed
      • Population Merge and Split
      • Varying Demographic Features
      • Population Events
      • Varying Genetic Features
      • Change of Mating Systems
      • Other
    • Other
      • Phenogenetic
      • Polygenic background
  • Interface
    • Command-line
    • Graphical User Interface
    • Integrated Development Environment
    • Script-based
    • Web-based
  • Development
    • Tested Platforms
      • Windows
      • Mac OS X
      • Linux and Unix
      • Solaris
      • Others
    • Language
      • C or C++
      • Java
      • R
      • Python
      • Perl
      • Visual Basic
      • Other
    • License
      • GNU Public License
      • BSD
      • Creative Commons
      • Other
  • GSR Certification
    • Accessibility
    • Documentation
    • Application
    • Support

Summary of Proposed Changes

Step 2: Review list of proposed attribute addition(s) and subtraction(s).

To Add

    To Remove

      Can't Find the Attribute You Are Looking For?

      If you would like to propose an attribute that you cannot find in the tree above, or if you would like to add a clarification to one or more attributes for this simulator (e.g. a specific file format for attribute /Output/File Format/Other), please list them in the Additional Comment box of the Submit tab.

      You may add citations by pmid, add citations by direct entry, remove citations (using the recycling bin icon), and edit citations (using the rarely seen edit icon) that were originally entered by direct entry.

      Summary of Proposed Changes

      To Add

      To Remove

      Current Citations/Applications

      Robinson, J.A., Brown, C., Kim, B.Y., Lohmueller, K.E., & Wayne, R.K., Purging of Strongly Deleterious Mutations Explains Long-Term Persistence and Absence of Inbreeding Depression in Island Foxes, Current Biology, 10-25-2018, https://doi.org/10.1016/j.cub.2018.08.066,, Application
      Rougemont, Q., Carrier, A., Leluyer, J., Ferchaud, A.-L., Farrell, J., Hatin, D., Brodeur, P., & Bernatchez, L., Combining population genomics and forward simulations to investigate stocking impacts: A case study of Muskellunge (Esox masquinongy) from the St. Lawrence River basin, bioRxiv, 07-06-2018, https://doi.org/10.1101/363283,, Application
      Cocca, M., Pybus, M., Palamara, P.F., et al., Purging of deleterious variants due to drift and founder effect in Italian populations with extended autozygosity, bioRxiv, 10-12-2015, https://doi.org/10.1101/022947,, Application
      Peyregne, S., Boyle, M.J., Dannemann, M., & Prufer, K., Detecting ancient positive selection in humans using extended lineage sorting, bioRxiv, 04-19-2017, https://doi.org/10.1101/092999,, Application
      Cassa, C.A., Weghorn, D., Balick, D.J., et al., Estimating the selective effect of heterozygous protein truncating variants from human exome data, bioRxiv, 09-16-2016, https://doi.org/10.1101/075523,, Application
      Aeschbacher, S., Packard Selby, J., Willis, J.H., & Coop, G., Population-genomic inference of the strength and timing of selection against gene flow, bioRxiv, 06-07-2017, https://doi.org/10.1101/072736,, Application
      Refoyo-Martínez, A., da Fonseca, R.R., Halldórsdóttir, K., Árnason, E., Mailund, T., & Racimo, F., Identifying loci under positive selection in complex population histories, bioRxiv, 10-25-2018, https://doi.org/10.1101/453092,, Application
      Matz, M.V., Treml, E.A., Aglyamova, G.V., et al., Potential for rapid genetic adaptation to warming in a Great Barrier Reef coral, bioRxiv, 06-18-2017, http://dx.doi.org/10.1101/114173,, Application
      Cahill, J.A., Heintzman, P.D., Harris, K., Teasdale, M., Kapp, J., Soares, A.E.R., Stirling, I., Bradley, D., Edwards, C.J., Kisleika, A.A., Malev, A.V., Monaghan, N., Green, R.E., Shapiro, B., Genomic evidence of globally widespread admixture from polar bears into brown bears during the last ice age, bioRxiv, 06-25-2017, https://doi.org/10.1101/154773,, Application
      Schiffels, S., Mustonen, V., & Lässig, M., The asexual genome of Drosophila, bioRxiv, 11-29-2017, https://doi.org/10.1101/226670,, Application
      Lange, J.D., & Pool, J.E., Impacts of recurrent hitchhiking on divergence and demographic inference in Drosophila, bioRxiv, 07-11-2018, http://dx.doi.org/10.1101/187633,, Application
      Laenen, B., Tedder, A., Nowak, M.D., et al., Demography and mating system shape the genome-wide impact of purifying selection in Arabis alpina, bioRxiv, 05-04-2017, http://dx.doi.org/10.1101/127209,, Application
      Harris, A.M., & DeGiorgio, M., Identifying and classifying shared selective sweeps from multilocus data, bioRxiv, 10-17-2018, https://doi.org/10.1101/446005,, Application
      de Koning, A.J., & De Sanctis, B.D., The Rate of Observable Molecular Evolution When Mutation May Not Be Weak, bioRxiv, 08-28-2018, https://doi.org/10.1101/259507,, Application
      Kiwoong, N.A.M., Nhim, S., Robin, S., Bretaudeau, A., & Negre, N., Genomic differentiation is initiated without physical linkage among targets of divergent selection in Fall armyworms, bioRxiv, 10-25-2018, https://doi.org/10.1101/452870,, Application
      Champer, J., Zhao, J., Champer, S., Liu, J., Messer, P.W., Population dynamics of underdominance gene drive systems in continuous space, bioRxiv, 10-22-2018, https://doi.org/10.1101/449355,, Application
      Cheng, X., & DeGiorgio, M., Detection of shared balancing selection in the absence of trans-species polymorphism, bioRxiv, 09-22-2018, https://doi.org/10.1101/320390,, Application
      Gazal, S., Loh, P.R., Finucane, H., Ganna, A., Schoech, A., Sunyaev, S., & Price, A., Low-frequency variant functional architectures reveal strength of negative selection across coding and non-coding annotations, bioRxiv, 04-09-2018, https://doi.org/10.1101/297572,, Application
      Harris, R., Sackman, A., & Jensen, J.D., On the unfounded enthusiasm for soft selective sweeps II: examining recent evidence from humans, flies, and viruses, bioRxiv, 10-19-2018, https://doi.org/10.1101/443051,, Application
      Hämälä, T., & Savolainen, O., Local adaptation under gene flow: Recombination, conditional neutrality and genetic trade-offs shape genomic patterns in Arabidopsis lyrata, bioRxiv, 07-23-2018, https://doi.org/10.1101/374900,, Application
      Li, H., & Ralph, P., Local PCA shows how the effect of population structure differs along the genome, bioRxiv, 09-19-2018, https://doi.org/10.1101/070615,, Application
      Mooney, J., Huber, C., Sul, J.H., Marsden, C., Zhang, Z., Sabatti, C., Ruiz-Linares, A., Bedoy, G., Costa Rica/Colombia Consortium for Genetic Investigation of Bipolar Endophenotypes, Freimer, N., & Lohmueller, K. E., Understanding the Hidden Complexity of Latin American Population Isolates, bioRxiv, 06-06-2018, https://doi.org/10.1101/340158,, Application
      Parada, J.L.C., & Charlesworth, B., The effects on neutral variability of recurrent selective sweeps and background selection, bioRxiv, 06-29-2018, https://doi.org/10.1101/358309,, Application
      Petr, M., Pääbo, S., Kelso, J., & Vernot, B., The limits of long-term selection against Neandertal introgression, bioRxiv, 07-04-2018, https://doi.org/10.1101/362566,, Application
      [Pubmed ID: 23341416], Kousathanas A, Keightley PD, A comparison of models to infer the distribution of fitness effects of new mutations., Genetics, 04-01-2013, https://doi.org/10.1101/022947,, Application
      [Pubmed ID: 23650353], Messer PW, Petrov DA, Frequent adaptation and the McDonald-Kreitman test., Proc Natl Acad Sci U S A, 05-21-2013, https://www.ncbi.nlm.nih.gov/pubmed/?term=23650353,, Application
      [Pubmed ID: 23709637], Messer PW, SLiM: simulating evolution with selection and linkage., Genetics, 08-01-2013, https://www.ncbi.nlm.nih.gov/pubmed/?term=23709637,Primary Citation
      [Pubmed ID: 24619126], Enard D, Messer PW, Petrov DA, Genome-wide signals of positive selection in human evolution., Genome Res, 06-01-2014, https://www.ncbi.nlm.nih.gov/pubmed/?term=24619126,, Application
      [Pubmed ID: 24830675], Veeramah KR, Gutenkunst RN, Woerner AE, Watkins JC, Hammer MF, Evidence for increased levels of positive and negative selection on the X chromosome versus autosomes in humans., Mol Biol Evol, 09-01-2014, https://www.ncbi.nlm.nih.gov/pubmed/?term=24830675,, Application
      [Pubmed ID: 24968283], Comeron JM, Background selection as baseline for nucleotide variation across the Drosophila genome., PLoS Genet, 06-01-2014, https://www.ncbi.nlm.nih.gov/pubmed/?term=24968283,, Application
      [Pubmed ID: 25375361], Bergland AO, Behrman EL, O'Brien KR, Schmidt PS, Petrov DA, Genomic evidence of rapid and stable adaptive oscillations over seasonal time scales in Drosophila., PLoS Genet, 11-01-2014, https://www.ncbi.nlm.nih.gov/pubmed/?term=25375361,, Application
      [Pubmed ID: 25552275], Arunkumar R, Ness RW, Wright SI, Barrett SC, The evolution of selfing is accompanied by reduced efficacy of selection and purging of deleterious mutations., Genetics, 03-01-2015, https://www.ncbi.nlm.nih.gov/pubmed/?term=25552275,, Application
      [Pubmed ID: 25685891], Hussin JG, Hodgkinson A, Idaghdour Y, Grenier JC, Goulet JP, Gbeha E, Hip-Ki E, Awadalla P, Recombination affects accumulation of damaging and disease-associated mutations in human populations., Nat Genet, 04-01-2015, https://www.ncbi.nlm.nih.gov/pubmed/?term=25685891,, Application
      [Pubmed ID: 25691747], Douglas GM, Gos G, Steige KA, Salcedo A, Holm K, Josephs EB, Arunkumar R, Ågren JA, Hazzouri KM, Wang W, Platts AE, et al., Hybrid origins and the earliest stages of diploidization in the highly successful recent polyploid Capsella bursa-pastoris., Proc Natl Acad Sci U S A, 03-03-2015, https://www.ncbi.nlm.nih.gov/pubmed/?term=25691747,, Application
      [Pubmed ID: 25827466], Bianco E, Soto HW, Vargas L, Pérez-Enciso M, The chimerical genome of Isla del Coco feral pigs (Costa Rica), an isolated population since 1793 but with remarkable levels of diversity., Mol Ecol, 05-01-2015, https://www.ncbi.nlm.nih.gov/pubmed/?term=25827466,, Application
      [Pubmed ID: 25941393], Assaf ZJ, Petrov DA, Blundell JR, Obstruction of adaptation in diploids by recessive, strongly deleterious alleles., Proc Natl Acad Sci U S A, 05-19-2015, https://www.ncbi.nlm.nih.gov/pubmed/?term=25941393,, Application
      [Pubmed ID: 26394805], Ewing GB, Jensen JD, The consequences of not accounting for background selection in demographic inference., Mol Ecol, 01-01-2016, https://www.ncbi.nlm.nih.gov/pubmed/?term=26394805,, Application
      [Pubmed ID: 26482794], Caballero A, Tenesa A, Keightley PD, The Nature of Genetic Variation for Complex Traits Revealed by GWAS and Regional Heritability Mapping Analyses., Genetics, 12-01-2015, https://www.ncbi.nlm.nih.gov/pubmed/?term=26482794,, Application
      [Pubmed ID: 26500260], Mafessoni F, Lachmann M, Selective Strolls: Fixation and Extinction in Diploids Are Slower for Weakly Selected Mutations Than for Neutral Ones., Genetics, 12-01-2015, https://www.ncbi.nlm.nih.gov/pubmed/?term=26500260,, Application
      [Pubmed ID: 26590212], Schrider DR, Kern AD, Inferring Selective Constraint from Population Genomic Data Suggests Recent Regulatory Turnover in the Human Brain., Genome Biol Evol, 11-19-2015, https://www.ncbi.nlm.nih.gov/pubmed/?term=26590212,, Application
      [Pubmed ID: 26596347], Racimo F, Testing for Ancient Selection Using Cross-population Allele Frequency Differentiation., Genetics, 02-01-2016, https://www.ncbi.nlm.nih.gov/pubmed/?term=26596347,, Application
      [Pubmed ID: 26752180], Galtier N, Adaptive Protein Evolution in Animals and the Effective Population Size Hypothesis., PLoS Genet, 01-01-2016, https://www.ncbi.nlm.nih.gov/pubmed/?term=26752180,, Application
      [Pubmed ID: 26831942], de Filippo C, Key FM, Ghirotto S, Benazzo A, Meneu JR, Weihmann A, Parra G, Green ED, Andrés AM, Recent Selection Changes in Human Genes under Long-Term Balancing Selection., Mol Biol Evol, 06-01-2016, https://www.ncbi.nlm.nih.gov/pubmed/?term=26831942,, Application
      [Pubmed ID: 27038113], Harris K, Nielsen R, The Genetic Cost of Neanderthal Introgression., Genetics, 06-01-2016, https://www.ncbi.nlm.nih.gov/pubmed/?term=27038113,, Application
      [Pubmed ID: 27187613], Enard D, Cai L, Gwennap C, Petrov DA, Viruses are a dominant driver of protein adaptation in mammals., Elife, 05-17-2016, https://www.ncbi.nlm.nih.gov/pubmed/?term=27187613,, Application
      [Pubmed ID: 27255481], Chen CY, Hung LY, Wu CS, Chuang TJ, Purifying selection shapes the coincident SNP distribution of primate coding sequences., Sci Rep, 06-03-2016, https://www.ncbi.nlm.nih.gov/pubmed/?term=27255481,, Application
      [Pubmed ID: 27702775], Haller BC, Messer PW, SLiM 2: Flexible, Interactive Forward Genetic Simulations., Mol Biol Evol, 01-01-2017, https://www.ncbi.nlm.nih.gov/pubmed/?term=27702775,Primary Citation
      [Pubmed ID: 27756828], Racimo F, Marnetto D, Huerta-Sánchez E, Signatures of Archaic Adaptive Introgression in Present-Day Human Populations., Mol Biol Evol, 02-01-2017, https://www.ncbi.nlm.nih.gov/pubmed/?term=27756828,, Application
      [Pubmed ID: 27845766], Lindo J, Huerta-Sánchez E, Nakagome S, Rasmussen M, Petzelt B, Mitchell J, Cybulski JS, Willerslev E, DeGiorgio M, Malhi RS, A time transect of exomes from a Native American population before and after European contact., Nat Commun, 11-15-2016, https://www.ncbi.nlm.nih.gov/pubmed/?term=27845766,, Application
      [Pubmed ID: 27903613], Pedersen CT, Lohmueller KE, Grarup N, Bjerregaard P, Hansen T, Siegismund HR, Moltke I, Albrechtsen A, The Effect of an Extreme and Prolonged Population Bottleneck on Patterns of Deleterious Variation: Insights from the Greenlandic Inuit., Genetics, 02-01-2017, https://www.ncbi.nlm.nih.gov/pubmed/?term=27903613,, Application
      [Pubmed ID: 28007980], Racimo F, Gokhman D, Fumagalli M, Ko A, Hansen T, Moltke I, Albrechtsen A, Carmel L, Huerta-Sánchez E, Nielsen R, Archaic Adaptive Introgression in TBX15/WARS2., Mol Biol Evol, 03-01-2017, https://www.ncbi.nlm.nih.gov/pubmed/?term=28007980,, Application
      [Pubmed ID: 28087781], Liu Q, Zhou Y, Morrell PL, Gaut BS, Deleterious Variants in Asian Rice and the Potential Cost of Domestication., Mol Biol Evol, 04-01-2017, https://www.ncbi.nlm.nih.gov/pubmed/?term=28087781,, Application
      [Pubmed ID: 28100590], Kardos M, Qvarnström A, Ellegren H, Inferring Individual Inbreeding and Demographic History from Segments of Identity by Descent in <i>Ficedula</i> Flycatcher Genome Sequences., Genetics, 03-01-2017, https://www.ncbi.nlm.nih.gov/pubmed/?term=28100590,, Application
      [Pubmed ID: 28137852], Nam K, Munch K, Mailund T, Nater A, Greminger MP, Krützen M, Marquès-Bonet T, Schierup MH, Evidence that the rate of strong selective sweeps increases with population size in the great apes., Proc Natl Acad Sci U S A, 02-14-2017, https://www.ncbi.nlm.nih.gov/pubmed/?term=28137852,, Application
      [Pubmed ID: 28249985], Kim BY, Huber CD, Lohmueller KE, Inference of the Distribution of Selection Coefficients for New Nonsynonymous Mutations Using Large Samples., Genetics, 05-01-2017, https://www.ncbi.nlm.nih.gov/pubmed/?term=28249985,, Application
      [Pubmed ID: 28253255], Rogers RL, Slatkin M, Excess of genomic defects in a woolly mammoth on Wrangel island., PLoS Genet, 03-02-2017, https://www.ncbi.nlm.nih.gov/pubmed/?term=28253255,, Application
      [Pubmed ID: 28275143], Bay RA, Ruegg K, Genomic islands of divergence or opportunities for introgression?, Proc Biol Sci, 03-15-2017, https://www.ncbi.nlm.nih.gov/pubmed/?term=28275143,, Application
      [Pubmed ID: 28341700], Haller BC, Messer PW, asymptoticMK: A Web-Based Tool for the Asymptotic McDonald-Kreitman Test., G3 (Bethesda), 05-05-2017, https://www.ncbi.nlm.nih.gov/pubmed/?term=28341700,, Application
      [Pubmed ID: 28400513], Huber CD, Kim BY, Marsden CD, Lohmueller KE, Determining the factors driving selective effects of new nonsynonymous mutations., Proc Natl Acad Sci U S A, 04-25-2017, https://www.ncbi.nlm.nih.gov/pubmed/?term=28400513,, Application
      [Pubmed ID: 28450643], Librado P, Gamba C, Gaunitz C, Der Sarkissian C, Pruvost M, Albrechtsen A, Fages A, Khan N, Schubert M, Jagannathan V, et al., Ancient genomic changes associated with domestication of the horse., Science, 04-28-2017, https://www.ncbi.nlm.nih.gov/pubmed/?term=28450643,, Application
      [Pubmed ID: 28473589], Sohail M, Vakhrusheva OA, Sul JH, Pulit SL, Francioli LC, Genome of the Netherlands Consortium., Alzheimer’s Disease Neuroimaging Initiative., van den Berg LH, Veldink JH, de Bakker PIW, et al., Negative selection in humans and fruit flies involves synergistic epistasis., Science, 05-05-2017, https://www.ncbi.nlm.nih.gov/pubmed/?term=28473589,, Application
      [Pubmed ID: 28751421], Booker TR, Ness RW, Keightley PD, The Recombination Landscape in Wild House Mice Inferred Using Population Genomic Data., Genetics, 09-01-2017, https://www.ncbi.nlm.nih.gov/pubmed/?term=28751421,, Application
      [Pubmed ID: 28892061], Gazal S, Finucane HK, Furlotte NA, Loh PR, Palamara PF, Liu X, Schoech A, Bulik-Sullivan B, Neale BM, Gusev A, et al., Linkage disequilibrium-dependent architecture of human complex traits shows action of negative selection., Nat Genet, 10-01-2017, https://www.ncbi.nlm.nih.gov/pubmed/?term=28892061,, Application
      [Pubmed ID: 28957509], Xu D, Pavlidis P, Taskent RO, Alachiotis N, Flanagan C, DeGiorgio M, Blekhman R, Ruhl S, Gokcumen O, Archaic Hominin Introgression in Africa Contributes to Functional Salivary MUC7 Genetic Variation., Mol Biol Evol, 10-01-2017, https://www.ncbi.nlm.nih.gov/pubmed/?term=28957509,, Application
      [Pubmed ID: 28981714], Siewert KM, Voight BF, Detecting Long-Term Balancing Selection Using Allele Frequency Correlation., Mol Biol Evol, 11-01-2017, https://www.ncbi.nlm.nih.gov/pubmed/?term=28981714,, Application
      [Pubmed ID: 28982795], Sikora M, Seguin-Orlando A, Sousa VC, Albrechtsen A, Korneliussen T, Ko A, Rasmussen S, Dupanloup I, Nigst PR, Bosch MD, et al., Ancient genomes show social and reproductive behavior of early Upper Paleolithic foragers., Science, 11-03-2017, https://www.ncbi.nlm.nih.gov/pubmed/?term=28982795,, Application
      [Pubmed ID: 29026132], Eichstaedt CA, Pagani L, Antao T, Inchley CE, Cardona A, Mörseburg A, Clemente FJ, Sluckin TJ, Metspalu E, Mitt M, et al., Evidence of Early-Stage Selection on EPAS1 and GPR126 Genes in Andean High Altitude Populations., Sci Rep, 10-12-2017, https://www.ncbi.nlm.nih.gov/pubmed/?term=29026132,, Application
      [Pubmed ID: 29029271], Morgan AP, Pardo-Manuel de Villena F, Sequence and Structural Diversity of Mouse Y Chromosomes., Mol Biol Evol, 12-01-2017, https://www.ncbi.nlm.nih.gov/pubmed/?term=29029271,, Application
      [Pubmed ID: 29069452], Kosheleva K, Desai MM, Recombination Alters the Dynamics of Adaptation on Standing Variation in Laboratory Yeast Populations., Mol Biol Evol, 01-01-2018, https://www.ncbi.nlm.nih.gov/pubmed/?term=29069452,, Application
      [Pubmed ID: 29109230], Comeron JM, Background selection as null hypothesis in population genomics: insights and challenges from <i>Drosophila</i> studies., Philos Trans R Soc Lond B Biol Sci, 12-19-2017, https://www.ncbi.nlm.nih.gov/pubmed/?term=29109230,, Application
      [Pubmed ID: 29113018], Cheng X, Xu C, DeGiorgio M, Fast and robust detection of ancestral selective sweeps., Mol Ecol, 12-01-2017, https://www.ncbi.nlm.nih.gov/pubmed/?term=29113018,, Application
      [Pubmed ID: 29285971], Antelope CX, Marnetto D, Casey F, Huerta-Sanchez E, Leveraging Multiple Populations across Time Helps Define Accurate Models of Human Evolution: A Reanalysis of the Lactase Persistence Adaptation., Hum Biol, 01-01-2017, https://www.ncbi.nlm.nih.gov/pubmed/?term=29285971,, Application
      [Pubmed ID: 29459708], Johnson KE, Voight BF, Patterns of shared signatures of recent positive selection across human populations., Nat Ecol Evol, 04-01-2018, https://www.ncbi.nlm.nih.gov/pubmed/?term=29459708,, Application
      [Pubmed ID: 29459739], Sugden LA, Atkinson EG, Fischer AP, Rong S, Henn BM, Ramachandran S, Localization of adaptive variants in human genomes using averaged one-dependence estimation., Nat Commun, 02-19-2018, https://www.ncbi.nlm.nih.gov/pubmed/?term=29459739,, Application
      [Pubmed ID: 29467190], Moon JM, Aronoff DM, Capra JA, Abbot P, Rokas A, Examination of Signatures of Recent Positive Selection on Genes Involved in Human Sialic Acid Biology., G3 (Bethesda), 03-28-2018, https://www.ncbi.nlm.nih.gov/pubmed/?term=29467190,, Application
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