a web server to simulate sequences with indel parameters inferred using an approximate Bayesian computation algorithm Long Description (required)
SpartaABC is an Approximate Bayesian Computation (ABC) reject algorithm to infer indel parameters from sequence data.
It focuses on the inference of three indel parameters: IR — the indel-to-substitution rate ratio, A — the shape parameter for the power law distribution controlling the indel length, and RL — the root length parameter.
SpartaABC extracts a vector of summary statistics from its input; it then performs repeated simulations using an integrated sequence simulator (Fletcher and Yang 2009, Cartwright 2016) under various indel parameters. From each such simulated dataset it extracts a vector of summary statistics and computes its distance from the vector extracted for the input using a weighted Euclidean distance. http://spartaabc.tau.ac.il/webserver bo.peng@bcm.edu
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[Pubmed ID: 28460062 ],
Ashkenazy H, Levy Karin E, Mertens Z, Cartwright RA, Pupko T ,
SpartaABC: a web server to simulate sequences with indel parameters inferred using an approximate Bayesian computation algorithm. ,
Nucleic Acids Res ,
07-03-2017 ,
https://www.ncbi.nlm.nih.gov/pubmed/?term=28460062, Primary Citation